Tsuguhito Ota : rechercher sur Z-Library

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1

Empagliflozin reverses obesity and insulin resistance through fat browning and alternative macrophage activation in mice fed a high-fat diet

Xu, Liang, Nagata, Naoto, Chen, Guanliang, Nagashimada, Mayumi, Zhuge, Fen, Ni, Yinhua, Sakai, Yuriko, Kaneko, Shuichi, Ota, Tsuguhito

Journal:

BMJ Open Diabetes Research & Care

Année:

2019

Fichier:

PDF, 7.31 MB

2019

2

391 - Circulating Extracellular Vesicle Encapsulated Long Noncoding RNA HULC would be a Potential Biomarker for Human Pancreatic Cancer

Takahashi, Kenji, Ota, Yu, Iwamoto, Hidetaka, Yamakita, Keisuke, Kitano, Yohei, Makino, Yuichi, Ota, Tsuguhito

Journal:

Gastroenterology

Année:

2018

Langue:

english

Fichier:

PDF, 754 KB

english, 2018

3

Regulation of Gut Microbiota and Metabolic Endotoxemia with Dietary Factors

Fuke, Nobuo, Nagata, Naoto, Suganuma, Hiroyuki, Ota, Tsuguhito

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 940 KB

english, 2019

4

Hypoxia-inducible factor-1α is the therapeutic target of the SGLT2 inhibitor for diabetic nephropathy

Bessho, Ryoichi, Takiyama, Yumi, Takiyama, Takao, Kitsunai, Hiroya, Takeda, Yasutaka, Sakagami, Hidemitsu, Ota, Tsuguhito

Journal:

Scientific Reports

Année:

2019

Langue:

english

Fichier:

PDF, 1.80 MB

english, 2019

5

Intake of Ï-6 Polyunsaturated Fatty Acid-Rich Vegetable Oils and Risk of Lifestyle Diseases

Yamashima, Tetsumori, Ota, Tsuguhito, Mizukoshi, Eishiro, Nakamura, Hiroyuki, Yamamoto, Yasuhiko, Kikuchi, Mitsuru, Yamashita, Tatsuya, Kaneko, Shuichi

Journal:

Advances in Nutrition: An International Review Journal

Année:

2020

Fichier:

PDF, 6.61 MB

2020

6

Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet

Naoto Matsuzawa, Toshinari Takamura, Seiichiro Kurita, Hirofumi Misu, Tsuguhito Ota, Hitoshi Ando, Masayoshi Yokoyama, Masao Honda, Yoh Zen, Yasuni Nakanuma, Ken-ichi Miyamoto, Shuichi Kaneko

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 1.75 MB

english, 2007

7

Tranilast, an antifibrogenic agent, ameliorates a dietary rat model of nonalcoholic steatohepatitis

Masafumi Uno, Seiichiro Kurita, Hirofumi Misu, Hitoshi Ando, Tsuguhito Ota, Naoto Matsuzawa-Nagata, Yuki Kita, Satoko Nabemoto, Hiroshi Akahori, Yoh Zen, Yasuni Nakanuma, Shuichi Kaneko, Toshinari Tak

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 2.65 MB

english, 2008

8

Liver steatosis, but not fibrosis, is associated with insulin resistance in nonalcoholic fatty liver disease

Masaru Sakurai, Toshinari Takamura, Tsuguhito Ota, Hitoshi Ando, Hiroshi Akahori, Kyosuke Kaji, Motoko Sasaki, Yasuni Nakanuma, Katsuyuki Miura, Shuichi Kaneko

Journal:

Journal of Gastroenterology

Année:

2007

Langue:

english

Fichier:

PDF, 142 KB

english, 2007

9

Obesity Upregulates Genes Involved in Oxidative Phosphorylation in Livers of Diabetic Patients

Toshinari Takamura, Hirofumi Misu, Naoto Matsuzawa-Nagata, Masaru Sakurai, Tsuguhito Ota, Akiko Shimizu, Seiichiro Kurita, Yumie Takeshita, Hitoshi Ando, Masao Honda, Shuichi Kaneko

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2008

10

Gender Differences in the Association between Anthropometric Indices of Obesity and Blood Pressure in Japanese

SAKURAI, Masaru, MIURA, Katsuyuki, TAKAMURA, Toshinari, OTA, Tsuguhito, ISHIZAKI, Masao, MORIKAWA, Yuko, KIDO, Teruhiko, NARUSE, Yuchi, NAKAGAWA, Hideaki

Journal:

Hypertension Research

Année:

2006

Langue:

english

Fichier:

PDF, 78 KB

english, 2006

11

Olmesartan ameliorates a dietary rat model of non-alcoholic steatohepatitis through its pleiotropic effects

Seiichiro Kurita, Toshinari Takamura, Tsuguhito Ota, Naoto Matsuzawa-Nagata, Yuki Kita, Masafumi Uno, Satoko Nabemoto, Kazuhide Ishikura, Hirofumi Misu, Hitoshi Ando, Yoh Zen, Yasuni Nakanuma, Shuichi

Journal:

European Journal of Pharmacology

Année:

2008

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2008

12

Increased oxidative stress precedes the onset of high-fat diet–induced insulin resistance and obesity

Naoto Matsuzawa-Nagata, Toshinari Takamura, Hitoshi Ando, Seiji Nakamura, Seiichiro Kurita, Hirofumi Misu, Tsuguhito Ota, Masayoshi Yokoyama, Masao Honda, Ken-ichi Miyamoto, Shuichi Kaneko

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 618 KB

english, 2008

13

Effect of pioglitazone on muscle sympathetic nerve activity in type 2 diabetes mellitus with alpha-glucosidase inhibitor

Daisuke Kobayashi, Masayuki Takamura, Hisayoshi Murai, Soichiro Usui, Tatsunori Ikeda, Jun-ichiro Inomata, Shin-ichiro Takashima, Takeshi Kato, Hiroshi Furusho, Yumie Takeshita, Tsuguhito Ota, Toshina

Journal:

Autonomic Neuroscience

Année:

2010

Langue:

english

Fichier:

PDF, 429 KB

english, 2010

14

Gene expression profiles in peripheral blood mononuclear cells reflect the pathophysiology of type 2 diabetes

Toshinari Takamura, Masao Honda, Yoshio Sakai, Hitoshi Ando, Akiko Shimizu, Tsuguhito Ota, Masaru Sakurai, Hirofumi Misu, Seiichiro Kurita, Naoto Matsuzawa-Nagata, Masahiro Uchikata, Seiji Nakamura, R

Journal:

Biochemical and Biophysical Research Communications

Année:

2007

Langue:

english

Fichier:

PDF, 143 KB

english, 2007

15

A Liver-Derived Secretory Protein, Selenoprotein P, Causes Insulin Resistance

Hirofumi Misu, Toshinari Takamura, Hiroaki Takayama, Hiroto Hayashi, Naoto Matsuzawa-Nagata, Seiichiro Kurita, Kazuhide Ishikura, Hitoshi Ando, Yumie Takeshita, Tsuguhito Ota, Masaru Sakurai, Tatsuya

Journal:

Cell Metabolism

Année:

2010

Langue:

english

Fichier:

PDF, 785 KB

english, 2010

16

Significance of IA-2 antibody in Japanese type 1 diabetes: its association with GAD antibody

Tsuguhito Ota, Toshinari Takamura, Yukihiro Nagai, Yukihiro Bando, Rika Usuda

Journal:

Diabetes Research and Clinical Practice

Année:

2005

Langue:

english

Fichier:

PDF, 88 KB

english, 2005

17

Factors associated with improvement of fasting plasma glucose level by mealtime dosing of a rapid-acting insulin analog in type 2 diabetes

Toshinari Takamura, Masaru Sakurai, Masumi Nakamura, Akiko Shimizu, Tsuguhito Ota, Hirofumi Misu, Yumie Takeshita, Naomi Tsuchiyama, Seiichiro Kurita, Hitoshi Ando, Shuichi Kaneko

Journal:

Diabetes Research and Clinical Practice

Année:

2007

Langue:

english

Fichier:

PDF, 163 KB

english, 2007

18

Tumor necrosis factor-α–induced production of plasminogen activator inhibitor 1 and its regulation by pioglitazone and cerivastatin in a nonmalignant human hepatocyte cell line

Yumie Takeshita, Toshinari Takamura, Erika Hamaguchi, Akiko Shimizu, Tsuguhito Ota, Masaru Sakurai, Shuichi Kaneko

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 259 KB

english, 2006

19

Pre-Obesity in WHO classification involves metabolic syndrome in Japanese

Tsuguhito Ota, Toshinari Takamura, Ken-Ichi Kobayashi, Nobuyuki Hirai, Syoichiro Hirose

Journal:

Diabetes Research and Clinical Practice

Année:

2000

Langue:

english

Fichier:

PDF, 94 KB

english, 2000

20

723 Differential gene expression in the liver of type 2 diabetic patients: features of atherosclerosis and NASH

Toshinari Takamura, Masao Honda, Masaru Sakurai, Tsuguhito Ota, Shuichi Kaneko

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 146 KB

english, 2003

21

Insulin Resistance Accelerates a Dietary Rat Model of Nonalcoholic Steatohepatitis

Tsuguhito Ota, Toshinari Takamura, Seiichiro Kurita, Naoto Matsuzawa, Yuki Kita, Masafumi Uno, Hiroshi Akahori, Hirofumi Misu, Masaru Sakurai, Yoh Zen, Yasuni Nakanuma, Shuichi Kaneko

Journal:

Gastroenterology

Année:

2007

Langue:

english

Fichier:

PDF, 1.95 MB

english, 2007

22

The effects of ezetimibe on non-alcoholic fatty liver disease and glucose metabolism: a randomised controlled trial

Takeshita, Yumie, Takamura, Toshinari, Honda, Masao, Kita, Yuki, Zen, Yoh, Kato, Ken-ichiro, Misu, Hirofumi, Ota, Tsuguhito, Nakamura, Mikiko, Yamada, Kazutoshi, Sunagozaka, Hajime, Arai, Kuniaki, Yam

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 276 KB

english, 2014

23

Selenoprotein P as a diabetes-associated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells

Ishikura, Kazuhide, Misu, Hirofumi, Kumazaki, Masafumi, Takayama, Hiroaki, Matsuzawa-Nagata, Naoto, Tajima, Natsumi, Chikamoto, Keita, Lan, Fei, Ando, Hitoshi, Ota, Tsuguhito, Sakurai, Masaru, Takeshi

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 703 KB

english, 2014

24

Measurement of Thyroid Blood Flow Area Is Useful for Diagnosing the Cause of Thyrotoxicosis

Kurita, Seiichiro, Sakurai, Masaru, Kita, Yuki, Ota, Tsuguhito, Ando, Hitoshi, Kaneko, Shuichi, Takamura, Toshinari

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 84 KB

english, 2005

25

CCR5

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 591 KB

english, 2013

26

Prevention and Reversal of Lipotoxicity-Induced Hepatic Insulin Resistance and Steatohepatitis in Mice by an Antioxidant Carotenoid, β-Cryptoxanthin

Ni, Yinhua, Nagashimada, Mayumi, Zhan, Lili, Nagata, Naoto, Kobori, Masuko, Sugiura, Minoru, Ogawa, Kazunori, Kaneko, Shuichi, Ota, Tsuguhito

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 2.47 MB

english, 2015

27

Obesity-Induced Inflammation and Insulin Resistance

Journal:

Frontiers in Endocrinology

Année:

2014

Langue:

english

Fichier:

PDF, 373 KB

english, 2014

28

Central Insulin Action Activates Kupffer Cells by Suppressing Hepatic Vagal Activation via the Nicotinic Alpha 7 Acetylcholine Receptor

Kimura, Kumi, Tanida, Mamoru, Nagata, Naoto, Inaba, Yuka, Watanabe, Hitoshi, Nagashimada, Mayumi, Ota, Tsuguhito, Asahara, Shun-ichiro, Kido, Yoshiaki, Matsumoto, Michihiro, Toshinai, Koji, Nakazato,

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.39 MB

english, 2016

29

DPP-4 inhibition by linagliptin attenuates obesity-related inflammation and insulin resistance by regulating M1/M2 macrophage polarization

Zhuge, Fen, Ni, Yinhua, Nagashimada, Mayumi, Nagata, Naoto, Xu, Liang, Mukaida, Naofumi, Kaneko, Shuichi, Ota, Tsuguhito

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 4.36 MB

english, 2016

30

Fatty liver as a consequence and cause of insulin resistance: Lessons from type 2 diabetic liver

Takamura, Toshinari, Misu, Hirofumi, Ota, Tsuguhito, Kaneko, Shuichi

Journal:

Endocrine Journal

Année:

2012

Langue:

english

Fichier:

PDF, 2.83 MB

english, 2012

31

Fulminating Onset Type 1 Diabetes with Positivity for Anti-GAD Antibody and Elevated Pancreatic Exocrine Enzyme Concentrations

KAHARA, Toshio, TAKAMURA, Toshinari, ANDO, Hitoshi, SAKURAI, Masara, OTA, Tsuguhito, MlSAKI, Tsuguho, OBA, Sakae, IGUCHI, Masahara, KOMORI, Kazutoshi, KOBAYASHI, Ken-ichi

Journal:

Internal Medicine

Année:

2003

Langue:

english

Fichier:

PDF, 692 KB

english, 2003

32

Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E

Ni, Yinhua, Nagashimada, Mayumi, Zhuge, Fen, Zhan, Lili, Nagata, Naoto, Tsutsui, Akemi, Nakanuma, Yasuni, Kaneko, Shuichi, Ota, Tsuguhito

Journal:

Scientific Reports

Année:

2015

Langue:

english

Fichier:

PDF, 3.11 MB

english, 2015

33

Metformin Prevents and Reverses Inflammation in a Non-Diabetic Mouse Model of Nonalcoholic Steatohepatitis

Kita, Yuki, Takamura, Toshinari, Misu, Hirofumi, Ota, Tsuguhito, Kurita, Seiichiro, Takeshita, Yumie, Uno, Masafumi, Matsuzawa-Nagata, Naoto, Kato, Ken-ichiro, Ando, Hitoshi, Fujimura, Akio, Hayashi,

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 3.37 MB

english, 2012

34

Astaxanthin prevents and reverses insulin resistance and steatohepatitis: A comparison with vitamin E

Xu, Liang, Ni, Yinhua, Nagashimada, Mayumi, Zhuge, Fen, Nagata, Naoto, Kaneko, Shuichi, Ota, Tsuguhito

Journal:

Diabetes Research and Clinical Practice

Année:

2016

Langue:

english

Fichier:

PDF, 37 KB

english, 2016

35

Comparison of acarbose versus voglibose monotherapy on GLP-1 secretion and postprandial dyslipidemia in patients with type 2 diabetes

Shima, Kosuke, Usuda, Rika, Ni, Yinhua, Kaneko, Shuichi, Takamura, Toshinari, Ota, Tsuguhito

Journal:

Diabetes Research and Clinical Practice

Année:

2016

Langue:

english

Fichier:

PDF, 51 KB

english, 2016

36

BETA-CRYPTOXANTHIN EXERTS BETTER CARDIOPROTECTION AGAINST CARDIAC ISCHEMIA-REPERFUSION INJURY THAN ASTAXANTHIN VIA PROTECTING MITOCHONDRIAL DYSFUNCTION IN MICE

Pongkan, Wanpitak, Xu, Liang, Takatori, Osamu, Nagata, Naoto, Ni, Yinhua, Nakayama, Mai, Chattipakorn, Siriporn, Usui, Soichiro, Ota, Tsuguhito, Chattipakorn, Nipon

Journal:

Journal of the American College of Cardiology

Année:

2017

Langue:

english

Fichier:

PDF, 890 KB

english, 2017

37

SGLT2 Inhibition by Empagliflozin Promotes Fat Utilization and Browning and Attenuates Inflammation and Insulin Resistance by Polarizing M2 Macrophages in Diet-induced Obese Mice

Xu, Liang, Nagata, Naoto, Nagashimada, Mayumi, Zhuge, Fen, Ni, Yinhua, Chen, Guanliang, Mayoux, Eric, Kaneko, Shuichi, Ota, Tsuguhito

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 5.16 MB

english, 2017

38

Immune regulation of glucose and lipid metabolism

Journal:

Diabetology International

Année:

2017

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2017

39

Emerging roles of SGLT2 inhibitors in obesity and insulin resistance: Focus on fat browning and macrophage polarization

Xu, Liang, Ota, Tsuguhito

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 997 KB

english, 2017

40

Protective effects of astaxanthin on a combination of D-‍galactose and jet lag-induced aging model in mice

Ni, Yinhua, Wu, Tao, Yang, Luna, Xu, Yang, Ota, Tsuguhito, Fu, Zhengwei

Journal:

Endocrine Journal

Année:

2018

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2018

41

Glucoraphanin: A broccoli sprout extract that ameliorates obesity-induced inflammation and insulin resistance

Xu, Liang, Nagata, Naoto, Ota, Tsuguhito

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.74 MB

english, 2018

42

Inverse Correlation between Serum Levels of Selenoprotein P and Adiponectin in Patients with Type 2 Diabetes

Misu, Hirofumi, Ishikura, Kazuhide, Kurita, Seiichiro, Takeshita, Yumie, Ota, Tsuguhito, Saito, Yoshiro, Takahashi, Kazuhiko, Kaneko, Shuichi, Takamura, Toshinari, Luque, Raul M.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 239 KB

english, 2012

43

β-Cryptoxanthin Alleviates Diet-Induced Nonalcoholic Steatohepatitis by Suppressing Inflammatory Gene Expression in Mice

Kobori, Masuko, Ni, Yinhua, Takahashi, Yumiko, Watanabe, Natsumi, Sugiura, Minoru, Ogawa, Kazunori, Nagashimada, Mayumi, Kaneko, Shuichi, Naito, Shigehiro, Ota, Tsuguhito, Aguila, Marcia B.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 2.50 MB

english, 2014

44

Roles of Chemokines and Chemokine Receptors in Obesity-Associated Insulin Resistance and Nonalcoholic Fatty Liver Disease

Xu, Liang, Kitade, Hironori, Ni, Yinhua, Ota, Tsuguhito

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2015

45

Micronutrient Antioxidants and Nonalcoholic Fatty Liver Disease

Chen, Guanliang, Ni, Yinhua, Nagata, Naoto, Xu, Liang, Ota, Tsuguhito

Journal:

International Journal of Molecular Sciences

Année:

2016

Langue:

english

Fichier:

PDF, 928 KB

english, 2016

46

Hepatic Transcriptome Profiles of Mice with Diet-Induced Nonalcoholic Steatohepatitis Treated with Astaxanthin and Vitamin E

Kobori, Masuko, Takahashi, Yumiko, Sakurai, Mutsumi, Ni, Yinhua, Chen, Guanliang, Nagashimada, Mayumi, Kaneko, Shuichi, Ota, Tsuguhito

Journal:

International Journal of Molecular Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 2.70 MB

english, 2017

47

Reply to the Letter to the Editor by Li et al.: Bioinformatics Analysis in Mice with Diet-Induced Nonalcoholic Steatohepatitis Treated with Astaxanthin and Vitamin E

Kobori, Masuko, Takahashi, Yumiko, Sakurai, Mutsumi, Ni, Yinhua, Chen, Guanliang, Nagashimada, Mayumi, Kaneko, Shuichi, Ota, Tsuguhito

Journal:

International Journal of Molecular Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 128 KB

english, 2017

48

Novel Action of Carotenoids on Non-Alcoholic Fatty Liver Disease: Macrophage Polarization and Liver Homeostasis

Ni, Yinhua, Zhuge, Fen, Nagashimada, Mayumi, Ota, Tsuguhito

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.88 MB

english, 2016

49

Chemokine Systems Link Obesity to Insulin Resistance

Journal:

Diabetes & Metabolism Journal

Année:

2013

Langue:

english

Fichier:

PDF, 561 KB

english, 2013

50

Nonalcoholic Fatty Liver Disease and Insulin Resistance: New Insights and Potential New Treatments

Kitade, Hironori, Chen, Guanliang, Ni, Yinhua, Ota, Tsuguhito

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2017